XILINGIO M 10/5/1000 TABLET
Category: Diabetes Medicines
Brand: Torrent Pharmaceuticals Ltd
Composition / Active Salts
Price: ₹138.72
MRP: ₹173.40 (20% OFF)
Inclusive of 5% GST
Pack Size: A pack of 10 Tablets
Availability: In Stock
Description
XILINGIO M 10/5/1000 TABLET is a combination medication that contains three active ingredients: Empagliflozin, Linagliptin, and Metformin. Empagliflozin belongs to the class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, which work by preventing the kidneys from reabsorbing glucose back into the bloodstream, thereby increasing glucose excretion in the urine. Linagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of incretin hormones, which stimulate the release of insulin and decrease the production of glucose in the liver. Metformin is a biguanide that decreases glucose production in the liver, increases insulin sensitivity, and thereby lowers blood glucose levels. The combination of these three medications provides a comprehensive approach to managing type 2 diabetes mellitus.
The XILINGIO M 10/5/1000 TABLET is specifically formulated to provide a dose of 10mg Empagliflozin, 5mg Linagliptin, and 1000mg Metformin per tablet. This combination allows for a synergistic effect, where the individual components work together to achieve better glycemic control than any one medication alone. The tablet is designed for oral administration, and the dosage is typically taken once daily, with or without food. The medication is indicated for use in adults with type 2 diabetes mellitus, and its efficacy and safety have been established in numerous clinical trials. The combination of Empagliflozin, Linagliptin, and Metformin has been shown to provide significant improvements in glycemic control, as measured by HbA1c levels, as well as reductions in body weight and blood pressure.
Uses & Indications
XILINGIO M 10/5/1000 TABLET is primarily used for the treatment of type 2 diabetes mellitus in adults. The medication is indicated for use as an adjunct to diet and exercise, to improve glycemic control in patients with type 2 diabetes. The combination of Empagliflozin, Linagliptin, and Metformin provides a comprehensive approach to managing the disease, by addressing multiple pathophysiological mechanisms that contribute to hyperglycemia. The medication is particularly useful in patients who have not achieved adequate glycemic control with metformin or other oral antidiabetic medications, and who require additional therapy to achieve their treatment goals.
The XILINGIO M 10/5/1000 TABLET may also be used in combination with other antidiabetic medications, such as sulfonylureas, thiazolidinediones, or insulin, to achieve better glycemic control. However, the use of the medication in combination with other SGLT2 inhibitors or DPP-4 inhibitors is not recommended, as this may increase the risk of adverse effects. The medication is not indicated for use in patients with type 1 diabetes mellitus, or in patients with diabetic ketoacidosis. In addition, the medication is not recommended for use in patients with severe renal impairment, or in patients with a history of hypersensitivity to any of the active ingredients.
Benefits
The XILINGIO M 10/5/1000 TABLET provides several benefits for patients with type 2 diabetes mellitus. One of the primary benefits of the medication is its ability to provide significant improvements in glycemic control, as measured by HbA1c levels. The combination of Empagliflozin, Linagliptin, and Metformin has been shown to reduce HbA1c levels by 1-2%, which is a clinically significant reduction. Additionally, the medication has been shown to reduce body weight and blood pressure, which are important risk factors for cardiovascular disease.
The XILINGIO M 10/5/1000 TABLET also provides benefits in terms of its safety and tolerability profile. The medication has been shown to have a low risk of hypoglycemia, which is a common adverse effect of many antidiabetic medications. Additionally, the medication has been shown to have a low risk of weight gain, which is a common adverse effect of many antidiabetic medications. The medication is also convenient to use, as it is administered once daily, and can be taken with or without food. Overall, the XILINGIO M 10/5/1000 TABLET provides a comprehensive approach to managing type 2 diabetes mellitus, and its benefits make it a valuable treatment option for patients with the disease.
Side Effects
The XILINGIO M 10/5/1000 TABLET may cause several side effects, including gastrointestinal adverse effects such as diarrhea, nausea, and vomiting. The medication may also cause increased urination, which is a common adverse effect of SGLT2 inhibitors. Additionally, the medication may cause hypoglycemia, although this is less common than with other antidiabetic medications. The medication may also cause allergic reactions, such as rash, itching, and anaphylaxis, although these are rare.
The XILINGIO M 10/5/1000 TABLET may also increase the risk of certain serious adverse effects, such as kidney damage, liver damage, and pancreatitis. The medication may also increase the risk of bone fractures, particularly in patients with a history of osteoporosis. Additionally, the medication may increase the risk of genital mycotic infections, particularly in patients with a history of such infections. The medication may also increase the risk of urinary tract infections, particularly in patients with a history of such infections. Patients should be monitored closely for these adverse effects, and the medication should be discontinued if any serious adverse effects occur.
How To Use
The XILINGIO M 10/5/1000 TABLET is administered orally, once daily, with or without food. The medication should be taken at the same time every day, to help maintain a consistent level of the medication in the bloodstream. The dosage of the medication should be adjusted based on the patient's response to treatment, and the medication should be titrated to achieve the desired level of glycemic control. The medication should be taken in combination with diet and exercise, to achieve optimal glycemic control.
The XILINGIO M 10/5/1000 TABLET should be stored at room temperature, away from moisture and light. The medication should be kept out of reach of children, and should be disposed of properly if it is no longer needed. Patients should be instructed to read the patient information leaflet carefully, and to ask their healthcare provider if they have any questions about the medication. Patients should also be instructed to report any adverse effects to their healthcare provider, and to seek medical attention immediately if they experience any serious adverse effects.
How It Works
The XILINGIO M 10/5/1000 TABLET works by combining the actions of three active ingredients: Empagliflozin, Linagliptin, and Metformin. Empagliflozin works by inhibiting the reabsorption of glucose in the kidneys, thereby increasing glucose excretion in the urine. Linagliptin works by increasing the levels of incretin hormones, which stimulate the release of insulin and decrease the production of glucose in the liver. Metformin works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood glucose levels.
The combination of these three mechanisms of action provides a comprehensive approach to managing type 2 diabetes mellitus. The XILINGIO M 10/5/1000 TABLET reduces glucose production in the liver, increases insulin sensitivity, and increases glucose excretion in the urine. The medication also has a synergistic effect, where the individual components work together to achieve better glycemic control than any one medication alone. The medication has been shown to provide significant improvements in glycemic control, as measured by HbA1c levels, as well as reductions in body weight and blood pressure.
Precautions
The XILINGIO M 10/5/1000 TABLET should be used with caution in patients with certain medical conditions, such as kidney disease, liver disease, and heart failure. The medication should also be used with caution in patients who are at risk of hypoglycemia, such as patients who are taking other antidiabetic medications or who have a history of hypoglycemia. The medication should be used with caution in patients who are at risk of genital mycotic infections, such as patients with a history of such infections.
The XILINGIO M 10/5/1000 TABLET should not be used in patients with severe renal impairment, or in patients with a history of hypersensitivity to any of the active ingredients. The medication should also not be used in patients with diabetic ketoacidosis, or in patients with type 1 diabetes mellitus. Patients should be monitored closely for adverse effects, and the medication should be discontinued if any serious adverse effects occur. The medication should be used in combination with diet and exercise, to achieve optimal glycemic control.
Warnings & Contraindications
The XILINGIO M 10/5/1000 TABLET should be used with caution in patients who are at risk of pancreatitis, such as patients with a history of pancreatitis or patients who are taking other medications that increase the risk of pancreatitis. The medication should also be used with caution in patients who are at risk of bone fractures, such as patients with a history of osteoporosis or patients who are taking other medications that increase the risk of bone fractures.
The XILINGIO M 10/5/1000 TABLET should be used with caution in patients who are at risk of urinary tract infections, such as patients with a history of such infections or patients who are taking other medications that increase the risk of urinary tract infections. Patients should be monitored closely for adverse effects, and the medication should be discontinued if any serious adverse effects occur. The medication should be used in combination with diet and exercise, to achieve optimal glycemic control. Patients should be instructed to report any adverse effects to their healthcare provider, and to seek medical attention immediately if they experience any serious adverse effects.
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