VILDANORM M 500 TABLET
Category: Diabetes Medicines
Brand: Ajanta Pharma Limited
Composition / Active Salts
Price: ₹99.85
MRP: ₹199.69 (50% OFF)
Inclusive of 5% GST
Pack Size: A pack of 15 Tablets
Availability: In Stock
Description
VILDANORM M 500 TABLET is a combination medication that contains two active ingredients: Metformin and Vildagliptin. Metformin belongs to the class of biguanides and is used to decrease glucose production in the liver, improve the body's sensitivity to insulin, and thereby lower blood sugar levels. Vildagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the amount of incretin hormones, which in turn increases insulin release in response to meals and decreases the amount of sugar made by the body. The combination of these two medications provides a synergistic effect in managing type 2 diabetes mellitus. The tablet is available in a strength of 500mg of Metformin and 50mg of Vildagliptin, making it a convenient option for patients who require both medications.
The combination of Metformin and Vildagliptin in VILDANORM M 500 TABLET offers several benefits, including improved glycemic control, reduced risk of hypoglycemia, and a favorable effect on body weight. Metformin has been shown to have a positive effect on cardiovascular outcomes, and Vildagliptin has been demonstrated to have a neutral effect on cardiovascular risk factors. The tablet is designed to be taken orally, once or twice daily, with or without food, making it easy to incorporate into a patient's daily routine. The medication is typically prescribed for patients with type 2 diabetes who are not adequately controlled on Metformin alone or who have contraindications to other antidiabetic medications. The dosage and administration of VILDANORM M 500 TABLET should be individualized based on the patient's response to therapy, renal function, and other factors.
Uses & Indications
VILDANORM M 500 TABLET is primarily used in the treatment of type 2 diabetes mellitus, a chronic condition characterized by high blood sugar levels due to insulin resistance or impaired insulin secretion. The medication is used to improve glycemic control, reduce the risk of complications associated with diabetes, and improve the quality of life for patients with this condition. The combination of Metformin and Vildagliptin in VILDANORM M 500 TABLET has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, a measure of long-term glycemic control, and in improving fasting plasma glucose levels. The medication can be used as monotherapy or in combination with other antidiabetic medications, such as sulfonylureas, thiazolidinediones, or insulin, to achieve optimal glycemic control.
The use of VILDANORM M 500 TABLET is also associated with several benefits, including a reduced risk of cardiovascular events, such as heart attacks, strokes, and deaths from cardiovascular disease. The medication has been shown to have a neutral effect on body weight, which is an important consideration for patients with type 2 diabetes who are often overweight or obese. Additionally, VILDANORM M 500 TABLET has been demonstrated to have a low risk of hypoglycemia, a common side effect of many antidiabetic medications. The medication can be used in a variety of patient populations, including those with renal impairment, although the dosage may need to be adjusted based on the patient's creatinine clearance. Overall, VILDANORM M 500 TABLET is a valuable treatment option for patients with type 2 diabetes who require a combination of Metformin and Vildagliptin to achieve optimal glycemic control.
Benefits
The use of VILDANORM M 500 TABLET is associated with several benefits, including improved glycemic control, reduced risk of hypoglycemia, and a favorable effect on body weight. The combination of Metformin and Vildagliptin in the medication provides a synergistic effect, allowing for more effective management of type 2 diabetes. The medication has been shown to reduce HbA1c levels, improve fasting plasma glucose levels, and decrease the risk of cardiovascular events. Additionally, VILDANORM M 500 TABLET has been demonstrated to have a neutral effect on body weight, which is an important consideration for patients with type 2 diabetes who are often overweight or obese. The medication can be used in a variety of patient populations, including those with renal impairment, although the dosage may need to be adjusted based on the patient's creatinine clearance.
The benefits of VILDANORM M 500 TABLET also extend to its ease of use and administration. The medication is available in a convenient tablet form, which can be taken orally, once or twice daily, with or without food. This makes it easy for patients to incorporate the medication into their daily routine, improving adherence and reducing the risk of medication errors. The medication is also available in a range of strengths, allowing for individualized dosing based on the patient's response to therapy and other factors. Overall, VILDANORM M 500 TABLET is a valuable treatment option for patients with type 2 diabetes, offering a range of benefits that can help improve glycemic control, reduce the risk of complications, and improve the quality of life.
Side Effects
VILDANORM M 500 TABLET, like all medications, can cause side effects in some patients. The most common side effects associated with the medication include gastrointestinal symptoms, such as diarrhea, nausea, vomiting, and abdominal pain. These side effects are usually mild to moderate in severity and may resolve on their own over time. In some cases, the side effects may be more severe, requiring medical attention. Other common side effects of VILDANORM M 500 TABLET include headache, dizziness, and increased risk of hypoglycemia when used in combination with other antidiabetic medications. The medication can also cause an increase in liver enzymes, which can be a sign of liver damage.
The side effects of VILDANORM M 500 TABLET can be managed through a variety of strategies, including dose adjustment, concomitant medication use, and lifestyle modifications. For example, patients who experience gastrointestinal symptoms may benefit from taking the medication with food or using an anti-emetic medication to reduce nausea and vomiting. Patients who experience hypoglycemia may need to adjust their diet or exercise routine to prevent low blood sugar levels. In some cases, the side effects may be severe enough to require discontinuation of the medication. It is essential for patients to report any side effects to their healthcare provider, who can provide guidance on managing the side effects and adjusting the treatment plan as needed. Regular monitoring of liver function, kidney function, and blood glucose levels can also help identify potential side effects early on.
How To Use
VILDANORM M 500 TABLET is typically taken orally, once or twice daily, with or without food. The dosage and administration of the medication should be individualized based on the patient's response to therapy, renal function, and other factors. The recommended starting dose is usually 500mg of Metformin and 50mg of Vildagliptin, taken twice daily. The dosage can be adjusted based on the patient's response to therapy, with a maximum daily dose of 2000mg of Metformin and 100mg of Vildagliptin. Patients should be instructed to take the medication at the same time every day, with or without food, to maintain a consistent level of the medication in the bloodstream.
The use of VILDANORM M 500 TABLET requires careful monitoring of blood glucose levels, liver function, and kidney function. Patients should be instructed to report any changes in their medical condition, including any new or worsening symptoms, to their healthcare provider. The medication should be stored in a cool, dry place, away from direct sunlight and moisture. Patients should also be advised to keep the medication out of reach of children and pets. In case of a missed dose, patients should be instructed to take the next dose as soon as possible, unless it is almost time for the next scheduled dose. In this case, the patient should skip the missed dose and continue with the regular dosing schedule.
How It Works
VILDANORM M 500 TABLET works by combining the effects of Metformin and Vildagliptin, two medications that have different mechanisms of action. Metformin decreases glucose production in the liver, improves the body's sensitivity to insulin, and thereby lowers blood sugar levels. Vildagliptin, on the other hand, increases the amount of incretin hormones, which in turn increases insulin release in response to meals and decreases the amount of sugar made by the body. The combination of these two medications provides a synergistic effect, allowing for more effective management of type 2 diabetes. The medication works by reducing the amount of glucose produced by the liver, improving the body's response to insulin, and increasing the amount of insulin released in response to meals.
The mechanism of action of VILDANORM M 500 TABLET involves several key pathways. Metformin works by inhibiting the production of glucose in the liver, which is the primary source of glucose in the bloodstream. Vildagliptin, on the other hand, works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which breaks down incretin hormones. By inhibiting DPP-4, Vildagliptin increases the amount of incretin hormones, which in turn increases insulin release in response to meals and decreases the amount of sugar made by the body. The combination of these two mechanisms of action provides a comprehensive approach to managing type 2 diabetes, allowing for improved glycemic control, reduced risk of complications, and improved quality of life.
Precautions
The use of VILDANORM M 500 TABLET requires several precautions, including careful monitoring of blood glucose levels, liver function, and kidney function. Patients should be instructed to report any changes in their medical condition, including any new or worsening symptoms, to their healthcare provider. The medication should be used with caution in patients with renal impairment, as the dosage may need to be adjusted based on the patient's creatinine clearance. Patients with liver disease should also be monitored closely, as the medication can cause an increase in liver enzymes. The medication should not be used in patients with type 1 diabetes, as it is not effective in managing this condition.
The precautions for VILDANORM M 500 TABLET also include the risk of hypoglycemia, particularly when used in combination with other antidiabetic medications. Patients should be instructed to recognize the signs and symptoms of hypoglycemia, including shakiness, dizziness, sweating, and confusion. Patients should also be advised to carry a source of glucose, such as glucose tablets or juice, with them at all times to treat hypoglycemia. The medication should be used with caution in patients with a history of pancreatitis, as the risk of pancreatitis may be increased. Patients should be instructed to report any signs or symptoms of pancreatitis, including abdominal pain, nausea, and vomiting, to their healthcare provider.
Warnings & Contraindications
The use of VILDANORM M 500 TABLET requires caution in several patient populations, including patients with renal impairment, liver disease, and a history of pancreatitis. The medication should be used with caution in patients with heart failure, as the risk of worsening heart failure may be increased. Patients should be instructed to report any changes in their medical condition, including any new or worsening symptoms, to their healthcare provider. The medication should not be used in patients with type 1 diabetes, as it is not effective in managing this condition. Patients with a history of hypersensitivity to Metformin or Vildagliptin should not use the medication, as the risk of an allergic reaction may be increased.
The caution for VILDANORM M 500 TABLET also includes the risk of lactic acidosis, a rare but serious side effect that can occur in patients with renal impairment or other risk factors. Patients should be instructed to report any signs or symptoms of lactic acidosis, including muscle pain, weakness, and difficulty breathing, to their healthcare provider. The medication should be used with caution in patients who are at risk of lactic acidosis, including patients with renal impairment, liver disease, and a history of pancreatitis. Patients should be advised to seek medical attention immediately if they experience any signs or symptoms of lactic acidosis. The medication should be used under the guidance of a healthcare provider, who can monitor the patient's condition and adjust the treatment plan as needed.
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