TENEWAL M TABLET
Category: Diabetes Medicines
Brand: Ajanta Pharma Limited
Composition / Active Salts
Price: ₹65.16
MRP: ₹130.31 (50% OFF)
Inclusive of 5% GST
Pack Size: A pack of 10 Tablets
Availability: In Stock
Description
TENEWAL M TABLET is a combination medication that contains two active ingredients: Metformin and Teneligliptin. Metformin is a biguanide antidiabetic agent that works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood sugar levels. Teneligliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of incretin hormones, which in turn stimulates the release of insulin and decreases the release of glucagon, resulting in a decrease in blood glucose levels. The combination of Metformin and Teneligliptin in TENEWAL M TABLET provides a synergistic effect, allowing for better control of blood sugar levels in patients with type 2 diabetes mellitus.
The dosage form of TENEWAL M TABLET is a tablet, which is designed for oral administration. Each tablet contains 500mg of Metformin and 20mg of Teneligliptin. The tablets are usually taken twice a day, with or without food, as directed by the healthcare provider. The medication should be swallowed whole, without crushing or chewing, to ensure proper absorption and to minimize the risk of gastrointestinal side effects. Patients are advised to take the medication at the same time every day, to maintain a consistent level of the medication in the body and to achieve optimal therapeutic effects. It is also important to note that TENEWAL M TABLET is not intended for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis.
Uses & Indications
TENEWAL M TABLET is primarily used for the treatment of type 2 diabetes mellitus in adults. The medication is designed to improve glycemic control, reduce the risk of microvascular complications, and decrease the risk of cardiovascular events associated with diabetes. The combination of Metformin and Teneligliptin in TENEWAL M TABLET has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, fasting plasma glucose (FPG) levels, and postprandial glucose (PPG) levels. The medication can be used as monotherapy or in combination with other antidiabetic agents, such as sulfonylureas, thiazolidinediones, or insulin, to achieve optimal glycemic control.
In addition to its antidiabetic effects, TENEWAL M TABLET may also have beneficial effects on cardiovascular risk factors. The medication has been shown to reduce body weight, improve lipid profiles, and decrease blood pressure in patients with type 2 diabetes. These effects may contribute to a reduced risk of cardiovascular events, such as heart attacks, strokes, and peripheral vascular disease. Furthermore, TENEWAL M TABLET may also have a positive impact on renal function, as it has been shown to reduce the risk of kidney disease and kidney failure in patients with type 2 diabetes. Overall, TENEWAL M TABLET is a valuable treatment option for patients with type 2 diabetes, offering a range of benefits that extend beyond glycemic control.
Benefits
The use of TENEWAL M TABLET has several benefits for patients with type 2 diabetes. One of the primary benefits is the improvement in glycemic control, which can reduce the risk of microvascular complications, such as diabetic retinopathy, nephropathy, and neuropathy. The medication has also been shown to reduce the risk of cardiovascular events, such as heart attacks, strokes, and peripheral vascular disease, which are major causes of morbidity and mortality in patients with diabetes. Additionally, TENEWAL M TABLET may have beneficial effects on body weight, lipid profiles, and blood pressure, which can further reduce the risk of cardiovascular disease.
Another benefit of TENEWAL M TABLET is its potential to improve renal function and reduce the risk of kidney disease. The medication has been shown to decrease the levels of urinary albumin, a marker of kidney damage, and to slow the progression of kidney disease in patients with type 2 diabetes. Furthermore, TENEWAL M TABLET may also have a positive impact on cognitive function, as it has been shown to improve cognitive performance and reduce the risk of dementia in patients with type 2 diabetes. Overall, the benefits of TENEWAL M TABLET make it a valuable treatment option for patients with type 2 diabetes, offering a range of benefits that extend beyond glycemic control and can improve overall health and well-being.
Side Effects
TENEWAL M TABLET, like all medications, can cause side effects in some patients. The most common side effects of the medication include gastrointestinal symptoms, such as diarrhea, nausea, vomiting, and abdominal pain. These side effects are usually mild and temporary, but they can be severe and persistent in some patients. Other common side effects of TENEWAL M TABLET include headache, dizziness, and hypoglycemia (low blood sugar). The risk of hypoglycemia is increased when TENEWAL M TABLET is used in combination with other antidiabetic agents, such as sulfonylureas or insulin.
In rare cases, TENEWAL M TABLET can cause more serious side effects, such as lactic acidosis, pancreatitis, and allergic reactions. Lactic acidosis is a rare but potentially life-threatening condition that can occur when the levels of lactic acid in the blood become too high. Pancreatitis is inflammation of the pancreas, which can cause severe abdominal pain, nausea, and vomiting. Allergic reactions to TENEWAL M TABLET can cause symptoms such as rash, itching, and difficulty breathing. Patients who experience any of these side effects should seek medical attention immediately, as they can be serious and potentially life-threatening. It is also important to note that TENEWAL M TABLET may interact with other medications, such as cimetidine, warfarin, and digoxin, which can increase the risk of side effects.
How To Use
TENEWAL M TABLET should be taken exactly as directed by the healthcare provider. The usual dosage is one tablet twice a day, with or without food. The tablets should be swallowed whole, without crushing or chewing, to ensure proper absorption and to minimize the risk of gastrointestinal side effects. Patients should take the medication at the same time every day, to maintain a consistent level of the medication in the body and to achieve optimal therapeutic effects. It is also important to note that TENEWAL M TABLET should not be taken with other medications that can increase the risk of lactic acidosis, such as metformin and topiramate.
In addition to taking the medication as directed, patients should also follow a healthy diet and exercise regularly to achieve optimal glycemic control. A healthy diet should include plenty of fruits, vegetables, whole grains, and lean protein sources, and should be low in added sugars, saturated fats, and sodium. Regular exercise, such as walking or jogging, can help to improve insulin sensitivity and reduce blood sugar levels. Patients should also monitor their blood sugar levels regularly, using a glucose meter, to ensure that the medication is working effectively and to make any necessary adjustments to the dosage or treatment plan. It is also important to keep track of any side effects and to report them to the healthcare provider, as they can be a sign of a more serious condition.
How It Works
TENEWAL M TABLET works by combining the effects of two active ingredients: Metformin and Teneligliptin. Metformin is a biguanide antidiabetic agent that works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood sugar levels. Metformin also has a mild effect on reducing the absorption of glucose from the gut. Teneligliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases the levels of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones stimulate the release of insulin and decrease the release of glucagon, resulting in a decrease in blood glucose levels.
The combination of Metformin and Teneligliptin in TENEWAL M TABLET provides a synergistic effect, allowing for better control of blood sugar levels in patients with type 2 diabetes. The medication works by targeting multiple pathways involved in glucose metabolism, including glucose production in the liver, insulin sensitivity, and glucose absorption from the gut. By reducing glucose production in the liver and increasing insulin sensitivity, TENEWAL M TABLET can help to lower blood sugar levels and improve glycemic control. The medication can also help to reduce the risk of microvascular complications, such as diabetic retinopathy, nephropathy, and neuropathy, and can decrease the risk of cardiovascular events, such as heart attacks, strokes, and peripheral vascular disease.
Precautions
Before taking TENEWAL M TABLET, patients should inform their healthcare provider about any medical conditions they have, including kidney disease, liver disease, or heart disease. The medication may not be suitable for patients with severe kidney disease or liver disease, as it can increase the risk of lactic acidosis and other serious side effects. Patients should also inform their healthcare provider about any medications they are taking, including other antidiabetic agents, as they can interact with TENEWAL M TABLET and increase the risk of side effects.
Patients should also be aware of the signs and symptoms of hypoglycemia (low blood sugar), which can occur when TENEWAL M TABLET is used in combination with other antidiabetic agents. The signs and symptoms of hypoglycemia include shakiness, dizziness, sweating, hunger, and confusion. Patients who experience any of these symptoms should seek medical attention immediately, as hypoglycemia can be serious and potentially life-threatening. It is also important to note that TENEWAL M TABLET may not be suitable for patients who are pregnant or breastfeeding, as the medication can pass into the breast milk and affect the baby.
Warnings & Contraindications
TENEWAL M TABLET should be used with caution in patients with certain medical conditions, including kidney disease, liver disease, and heart disease. The medication can increase the risk of lactic acidosis, a rare but potentially life-threatening condition that can occur when the levels of lactic acid in the blood become too high. Patients with kidney disease or liver disease may be at increased risk of lactic acidosis, as they may have impaired clearance of the medication. Patients with heart disease may also be at increased risk of cardiovascular events, such as heart attacks, strokes, and peripheral vascular disease, when taking TENEWAL M TABLET.
Patients should also be cautious when taking TENEWAL M TABLET in combination with other medications, as they can interact with the medication and increase the risk of side effects. For example, the use of TENEWAL M TABLET with other antidiabetic agents, such as sulfonylureas or insulin, can increase the risk of hypoglycemia. The use of TENEWAL M TABLET with certain medications, such as cimetidine or warfarin, can also increase the risk of lactic acidosis and other serious side effects. Patients should inform their healthcare provider about any medications they are taking, and should seek medical attention immediately if they experience any signs or symptoms of side effects.
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