METKIN 500 SR TABLET
Category: Diabetes Medicines
Brand: Ajanta Pharma Limited
Composition / Active Salts
Price: ₹127.13
MRP: ₹423.75 (70% OFF)
Inclusive of 5% GST
Pack Size: A pack of 20 Tablets
Availability: In Stock
Description
Metkin 500 SR Tablet is a medication that contains the active ingredient Metformin, which is a biguanide class of oral antidiabetic drugs. It is used to treat type 2 diabetes mellitus, particularly in patients who are unable to control their blood sugar levels through diet and exercise alone. The medication works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood sugar levels. Metkin 500 SR Tablet is an extended-release formulation, which means that it releases the active ingredient slowly over a period of time, providing a steady and consistent effect. This formulation is designed to reduce the frequency of dosing and improve patient compliance.
The composition of Metkin 500 SR Tablet includes Metformin hydrochloride as the active ingredient, which is present in a strength of 500mg per tablet. The tablet also contains inactive ingredients such as microcrystalline cellulose, hypromellose, and magnesium stearate, which are used as fillers, binders, and lubricants to facilitate the manufacturing process. The tablet is designed to be taken orally, once or twice a day, with or without food, as directed by the healthcare provider. It is essential to follow the prescribed dosage and administration instructions carefully to ensure the safe and effective use of the medication. Patients should also be aware of the potential interactions between Metkin 500 SR Tablet and other medications, as well as any underlying medical conditions that may affect the use of the medication.
Uses & Indications
Metkin 500 SR Tablet is primarily used to treat type 2 diabetes mellitus, a condition characterized by high blood sugar levels due to insulin resistance or impaired insulin secretion. The medication is often prescribed as a monotherapy or in combination with other antidiabetic agents, such as sulfonylureas, thiazolidinediones, or insulin, to achieve better glycemic control. Metformin, the active ingredient in Metkin 500 SR Tablet, has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, a measure of average blood glucose control over a period of time. By lowering blood sugar levels, Metkin 500 SR Tablet can help prevent or delay the onset of complications associated with diabetes, such as cardiovascular disease, kidney damage, and nerve damage.
In addition to its use in the treatment of type 2 diabetes, Metkin 500 SR Tablet may also be prescribed for other conditions, such as polycystic ovary syndrome (PCOS), a hormonal disorder that can cause insulin resistance and high blood sugar levels. The medication may also be used to treat gestational diabetes, a condition that occurs during pregnancy and is characterized by high blood sugar levels. Furthermore, Metkin 500 SR Tablet may be prescribed for the treatment of obesity, as it has been shown to aid in weight loss and improve insulin sensitivity. However, it is essential to note that the medication should only be used under the guidance of a healthcare provider, as it may not be suitable for all patients, particularly those with certain medical conditions or taking certain medications.
Benefits
The use of Metkin 500 SR Tablet has several benefits, particularly in the treatment of type 2 diabetes. One of the primary advantages of the medication is its ability to lower blood sugar levels, which can help prevent or delay the onset of complications associated with diabetes. By reducing glucose production in the liver and increasing insulin sensitivity, Metkin 500 SR Tablet can help improve glycemic control, reducing the risk of cardiovascular disease, kidney damage, and nerve damage. Additionally, the medication has been shown to have a positive effect on weight, as it can aid in weight loss and improve body mass index (BMI).
Another benefit of Metkin 500 SR Tablet is its relatively low risk of hypoglycemia, a condition characterized by abnormally low blood sugar levels. Unlike some other antidiabetic medications, such as sulfonylureas, Metkin 500 SR Tablet does not stimulate insulin secretion, reducing the risk of hypoglycemia. This makes it a safer option for patients who are at risk of hypoglycemia, such as the elderly or those with a history of hypoglycemic episodes. Furthermore, Metkin 500 SR Tablet has been shown to have a positive effect on lipid profiles, reducing triglycerides and low-density lipoprotein (LDL) cholesterol, which can help reduce the risk of cardiovascular disease. Overall, the benefits of Metkin 500 SR Tablet make it a valuable treatment option for patients with type 2 diabetes.
Side Effects
Metkin 500 SR Tablet, like all medications, can cause side effects in some patients. The most common side effects associated with the medication include gastrointestinal symptoms, such as diarrhea, nausea, vomiting, and abdominal pain. These side effects are usually mild and temporary, resolving on their own within a few days of treatment. However, in some cases, they can be more severe and may require medical attention. Other common side effects of Metkin 500 SR Tablet include metallic taste, headache, and dizziness.
In rare cases, Metkin 500 SR Tablet can cause more serious side effects, such as lactic acidosis, a condition characterized by the buildup of lactic acid in the blood. This can occur in patients with kidney or liver disease, as well as those who are taking certain medications, such as iodinated contrast agents. Patients who experience symptoms such as muscle pain, weakness, or difficulty breathing should seek medical attention immediately, as these can be signs of lactic acidosis. Additionally, Metkin 500 SR Tablet can cause hypoglycemia, particularly when used in combination with other antidiabetic medications. Patients should be aware of the signs and symptoms of hypoglycemia, such as shakiness, sweating, and confusion, and should seek medical attention if they experience any of these symptoms.
How To Use
To use Metkin 500 SR Tablet safely and effectively, patients should follow the prescribed dosage and administration instructions carefully. The medication is typically taken orally, once or twice a day, with or without food, as directed by the healthcare provider. It is essential to swallow the tablet whole, without crushing or chewing, to ensure the slow and consistent release of the active ingredient. Patients should also be aware of the potential interactions between Metkin 500 SR Tablet and other medications, as well as any underlying medical conditions that may affect the use of the medication.
Patients should take Metkin 500 SR Tablet at the same time every day, to help establish a routine and improve adherence to the medication regimen. It is also essential to monitor blood sugar levels regularly, using a glucose meter or other testing device, to assess the effectiveness of the medication and make any necessary adjustments to the dosage or administration schedule. Additionally, patients should be aware of the signs and symptoms of hypoglycemia and lactic acidosis, and should seek medical attention immediately if they experience any of these symptoms. By following the prescribed instructions and being aware of the potential side effects and interactions, patients can use Metkin 500 SR Tablet safely and effectively to manage their type 2 diabetes.
How It Works
Metkin 500 SR Tablet works by decreasing glucose production in the liver and increasing insulin sensitivity, thereby lowering blood sugar levels. The active ingredient, Metformin, inhibits the production of glucose in the liver by reducing the activity of enzymes involved in gluconeogenesis, a process by which the liver produces glucose from non-carbohydrate sources. This reduction in glucose production helps to lower blood sugar levels, particularly in patients with type 2 diabetes who have impaired insulin secretion or insulin resistance.
In addition to its effects on glucose production, Metkin 500 SR Tablet also increases insulin sensitivity, allowing glucose to enter cells more efficiently. This is achieved through the activation of AMP-activated protein kinase (AMPK), an enzyme that plays a key role in regulating glucose and lipid metabolism. By increasing insulin sensitivity, Metkin 500 SR Tablet helps to improve glycemic control, reducing the risk of complications associated with diabetes, such as cardiovascular disease, kidney damage, and nerve damage. The medication also has a positive effect on lipid profiles, reducing triglycerides and LDL cholesterol, which can help reduce the risk of cardiovascular disease.
Precautions
Before taking Metkin 500 SR Tablet, patients should be aware of certain precautions to ensure the safe and effective use of the medication. One of the most important precautions is to inform the healthcare provider about any underlying medical conditions, such as kidney or liver disease, as these can affect the use of the medication. Patients should also inform their healthcare provider about any medications they are taking, including prescription and over-the-counter medications, as well as any herbal supplements or vitamins.
Patients with kidney disease should use Metkin 500 SR Tablet with caution, as the medication can increase the risk of lactic acidosis, a condition characterized by the buildup of lactic acid in the blood. Patients with liver disease should also use the medication with caution, as it can increase the risk of liver damage. Additionally, patients who are taking iodinated contrast agents, such as those used in imaging studies, should inform their healthcare provider, as these can increase the risk of lactic acidosis. Patients should also be aware of the signs and symptoms of hypoglycemia and lactic acidosis, and should seek medical attention immediately if they experience any of these symptoms.
Warnings & Contraindications
Patients should exercise caution when taking Metkin 500 SR Tablet, particularly in certain situations. For example, patients who are at risk of hypoglycemia, such as the elderly or those with a history of hypoglycemic episodes, should be cautious when taking the medication, particularly when used in combination with other antidiabetic medications. Patients who are taking medications that can increase the risk of lactic acidosis, such as iodinated contrast agents, should also exercise caution when taking Metkin 500 SR Tablet.
Patients should also be cautious when taking Metkin 500 SR Tablet if they have any underlying medical conditions, such as kidney or liver disease, as these can affect the use of the medication. Additionally, patients who are pregnant or breastfeeding should exercise caution when taking the medication, as its safety and efficacy in these populations have not been established. Patients should inform their healthcare provider if they experience any side effects or have any concerns about the medication, and should seek medical attention immediately if they experience any signs or symptoms of lactic acidosis or hypoglycemia. By exercising caution and being aware of the potential risks and benefits, patients can use Metkin 500 SR Tablet safely and effectively to manage their type 2 diabetes.
Generic Alternatives
- ZOMET 500MG TABLET — ₹9.53 | Intas Pharmaceuticals Ltd
- METMIN 10 TABLET — ₹11.64 | Jenburkt Pharmaceuticals Ltd
- BIGOMET 500MG 10 TABLET — ₹12.69 | Aristo Pharmaceuticals Pvt Ltd
- BIGOMET 500MG TABLET — ₹12.90 | Aristo Pharmaceuticals Pvt Ltd
- METMIN TABLET — ₹13.78 | Jenburkt Pharmaceuticals Ltd
- ZOFORM SR 500MG 10 TABLET — ₹15.26 | FDC Ltd
- ZOFORM SR 500MG TABLET — ₹15.26 | FDC Ltd
- BIGOMET SR 500MG STRIP OF 10 TABLET — ₹15.72 | Aristo Pharmaceuticals Pvt Ltd
- METLONG 500MG STRIP OF 10 TABLETS — ₹15.94 | Mankind Pharma Ltd
- METLONG 500 TAB — ₹16.20 | PANACEA BIOTEC LTD