GLUFLOZIN 10 MG TABLET
Category: Diabetes Medicines
Brand: Aristo Pharmaceuticals Pvt Ltd
Composition / Active Salts
Price: ₹138.74
MRP: ₹173.43 (20% OFF)
Inclusive of 5% GST
Pack Size: A pack of 15 Tablets
Availability: In Stock
Description
Dapagliflozin, the active ingredient in Gluflozin 10 mg tablet, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the blood, thereby increasing the amount of glucose excreted in the urine. This mechanism of action helps to lower blood glucose levels in patients with type 2 diabetes. The tablet is typically taken once daily, with or without food, and is often used in conjunction with other medications, such as metformin or sulfonylureas, to achieve optimal blood glucose control. Gluflozin 10 mg tablet is a film-coated tablet that is designed to be easy to swallow and minimize gastrointestinal side effects.
The composition of Gluflozin 10 mg tablet includes the active ingredient dapagliflozin, as well as inactive ingredients such as microcrystalline cellulose, anhydrous lactose, and magnesium stearate. The tablet is manufactured using a process that ensures the active ingredient is evenly distributed throughout the tablet, providing a consistent dose of dapagliflozin with each administration. The tablet's film coating helps to protect the active ingredient from degradation and ensures that it is released slowly and consistently over time. This helps to maintain a steady level of dapagliflozin in the bloodstream, providing optimal blood glucose control throughout the day. Additionally, the tablet's formulation is designed to minimize the risk of gastrointestinal side effects, such as nausea and diarrhea, which are common with other diabetes medications.
Uses & Indications
Gluflozin 10 mg tablet is primarily used to treat type 2 diabetes in adults. It is often prescribed in conjunction with other medications, such as metformin or sulfonylureas, to help lower blood glucose levels and improve glycemic control. The medication is also used to reduce the risk of major adverse cardiovascular events, such as heart attack, stroke, and death, in patients with type 2 diabetes and established cardiovascular disease. Additionally, Gluflozin 10 mg tablet may be used to treat other conditions, such as diabetic nephropathy, which is a type of kidney disease that can occur in patients with diabetes. The medication's ability to increase glucose excretion in the urine helps to reduce the amount of glucose that is reabsorbed into the bloodstream, which can help to slow the progression of kidney disease.
Gluflozin 10 mg tablet may also be used to treat patients with type 2 diabetes who have not responded adequately to other medications, such as metformin or sulfonylureas. In these cases, the medication may be used as a monotherapy or in combination with other medications to achieve optimal blood glucose control. The medication's unique mechanism of action, which involves inhibiting the SGLT2 transporter in the kidneys, makes it an effective treatment option for patients with type 2 diabetes who have not responded to other medications. Additionally, Gluflozin 10 mg tablet has been shown to have a favorable safety profile, with a low risk of hypoglycemia and other serious side effects, making it a popular treatment option for patients with type 2 diabetes.
Benefits
The use of Gluflozin 10 mg tablet has been shown to have several benefits for patients with type 2 diabetes. One of the primary benefits is its ability to lower blood glucose levels and improve glycemic control. This can help to reduce the risk of complications associated with diabetes, such as heart disease, kidney disease, and nerve damage. Additionally, Gluflozin 10 mg tablet has been shown to have a favorable effect on weight, with many patients experiencing weight loss as a result of taking the medication. This can help to improve overall health and reduce the risk of other health problems, such as high blood pressure and high cholesterol.
Another benefit of Gluflozin 10 mg tablet is its ability to reduce the risk of major adverse cardiovascular events, such as heart attack, stroke, and death. This is particularly important for patients with type 2 diabetes who have established cardiovascular disease, as they are at increased risk of these events. The medication's unique mechanism of action, which involves inhibiting the SGLT2 transporter in the kidneys, helps to reduce the amount of glucose that is reabsorbed into the bloodstream, which can help to reduce the risk of cardiovascular events. Additionally, Gluflozin 10 mg tablet has been shown to have a favorable safety profile, with a low risk of hypoglycemia and other serious side effects, making it a popular treatment option for patients with type 2 diabetes.
Side Effects
Gluflozin 10 mg tablet, like all medications, can cause side effects in some patients. One of the most common side effects is increased urination, which can occur as a result of the medication's mechanism of action. This can lead to dehydration and electrolyte imbalances, particularly in patients who are not drinking enough fluids. Other common side effects include yeast infections, such as vulvovaginitis and balanitis, which can occur as a result of the increased glucose in the urine. Additionally, some patients may experience gastrointestinal side effects, such as nausea and diarrhea, although these are generally mild and temporary.
More serious side effects can also occur, although these are rare. One of the most serious side effects is diabetic ketoacidosis, a condition that occurs when the body produces high levels of ketones, which can be life-threatening if left untreated. Other serious side effects include kidney problems, such as acute kidney injury, and increased risk of amputations, particularly in patients with a history of peripheral artery disease. Additionally, some patients may experience hypersensitivity reactions, such as anaphylaxis, which can be life-threatening if not treated promptly. It is essential for patients to report any side effects to their healthcare provider, as they can help to manage and minimize the risk of these events.
How To Use
Gluflozin 10 mg tablet is typically taken once daily, with or without food. It is essential to take the medication at the same time each day to maintain a consistent level of dapagliflozin in the bloodstream. Patients should swallow the tablet whole, without crushing or chewing, to minimize the risk of gastrointestinal side effects. Additionally, patients should drink plenty of fluids while taking the medication to help prevent dehydration and electrolyte imbalances. It is also essential to monitor blood glucose levels regularly, as the medication may need to be adjusted to achieve optimal glycemic control.
Patients should also be aware of the signs and symptoms of hypoglycemia, such as shakiness, dizziness, and confusion, and know how to treat them. This may involve consuming glucose tablets or glucose-rich foods, such as fruit juice or candy, to help raise blood glucose levels. Additionally, patients should be aware of the signs and symptoms of more serious side effects, such as diabetic ketoacidosis, and seek medical attention immediately if they occur. It is also essential to follow the healthcare provider's instructions for taking the medication, as they can help to minimize the risk of side effects and ensure optimal blood glucose control.
How It Works
Gluflozin 10 mg tablet works by inhibiting the SGLT2 transporter in the kidneys, which helps to reduce the amount of glucose that is reabsorbed into the bloodstream. This increases the amount of glucose that is excreted in the urine, which can help to lower blood glucose levels and improve glycemic control. The medication's mechanism of action is unique, as it does not involve increasing insulin production or enhancing insulin sensitivity, like other diabetes medications. Instead, it works by reducing the amount of glucose that is reabsorbed into the bloodstream, which can help to reduce the risk of hypoglycemia and other side effects.
The SGLT2 transporter is responsible for reabsorbing approximately 90% of the glucose that is filtered by the kidneys. By inhibiting this transporter, Gluflozin 10 mg tablet can increase the amount of glucose that is excreted in the urine, which can help to lower blood glucose levels. The medication's ability to reduce glucose reabsorption in the kidneys also helps to reduce the amount of glucose that is available for absorption into the bloodstream, which can help to reduce the risk of cardiovascular events. Additionally, the medication's unique mechanism of action makes it an effective treatment option for patients with type 2 diabetes who have not responded to other medications.
Precautions
Patients taking Gluflozin 10 mg tablet should be aware of several precautions to minimize the risk of side effects. One of the most important precautions is to drink plenty of fluids while taking the medication to help prevent dehydration and electrolyte imbalances. Additionally, patients should monitor their blood glucose levels regularly to ensure that the medication is working effectively and to minimize the risk of hypoglycemia. Patients should also be aware of the signs and symptoms of more serious side effects, such as diabetic ketoacidosis, and seek medical attention immediately if they occur.
Patients with a history of kidney disease or kidney problems should use Gluflozin 10 mg tablet with caution, as the medication may worsen these conditions. Additionally, patients with a history of liver disease or liver problems should use the medication with caution, as it may worsen these conditions. Patients should also be aware of the potential for interactions with other medications, such as diuretics and blood thinners, and inform their healthcare provider of all medications they are taking. Additionally, patients should not take Gluflozin 10 mg tablet if they are pregnant or breastfeeding, as the medication may harm the fetus or baby.
Warnings & Contraindications
Gluflozin 10 mg tablet should be used with caution in patients with certain medical conditions, such as kidney disease, liver disease, and heart disease. Patients with these conditions should be closely monitored by their healthcare provider while taking the medication to minimize the risk of side effects. Additionally, patients should be aware of the potential for interactions with other medications and inform their healthcare provider of all medications they are taking. Patients should also be aware of the signs and symptoms of more serious side effects, such as diabetic ketoacidosis, and seek medical attention immediately if they occur.
Patients should not take Gluflozin 10 mg tablet if they have a history of severe hypersensitivity reactions to dapagliflozin or any of the medication's inactive ingredients. Additionally, patients should not take the medication if they have a history of diabetic ketoacidosis or if they are at increased risk of developing diabetic ketoacidosis. Patients should also be aware of the potential for increased risk of amputations, particularly in patients with a history of peripheral artery disease, and inform their healthcare provider if they experience any symptoms of amputation, such as pain or numbness in the legs or feet. Patients should follow their healthcare provider's instructions for taking the medication and report any side effects or concerns to their healthcare provider.
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