EMPEXEL 10 TABLET

EMPEXEL 10 TABLET

Category: Diabetes Medicines

Brand: ABBOTT HEALTHCARE PVT LTD

Composition / Active Salts

Price: ₹112.50

MRP: ₹140.63 (20% OFF)

Inclusive of 5% GST

Pack Size: A pack of 15 Tablets

Availability: In Stock

Description

Empagliflozin, the active ingredient in EMPEXEL 10 TABLET, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It is used in the treatment of type 2 diabetes mellitus. The medication works by reducing glucose reabsorption in the kidneys, thereby increasing glucose excretion in the urine. This mechanism of action helps to lower blood glucose levels in patients with type 2 diabetes. EMPEXEL 10 TABLET is available in a strength of 10mg, which is a commonly prescribed dose for the management of type 2 diabetes. The tablet is usually taken once daily, with or without food, and it is essential to follow the dosage instructions provided by the healthcare provider to achieve optimal therapeutic effects. The composition of EMPEXEL 10 TABLET includes empagliflozin as the active ingredient, along with inactive ingredients such as microcrystalline cellulose, lactose monohydrate, and magnesium stearate. The tablet is designed to be easy to swallow and is usually taken orally. The medication is contraindicated in patients with a history of severe renal impairment, as well as those with a history of diabetic ketoacidosis. It is essential to monitor renal function and urine glucose levels regularly while taking EMPEXEL 10 TABLET to minimize the risk of adverse effects. Additionally, patients should be aware of the potential for hypoglycemia, particularly when empagliflozin is used in combination with other antidiabetic medications.

Uses & Indications

EMPEXEL 10 TABLET is primarily used in the treatment of type 2 diabetes mellitus. The medication is designed to improve glycemic control, reduce the risk of cardiovascular events, and slow the progression of kidney disease in patients with type 2 diabetes. Empagliflozin has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, which is a measure of average blood glucose control over time. The medication can be used as monotherapy or in combination with other antidiabetic medications, such as metformin, sulfonylureas, or insulin. EMPEXEL 10 TABLET is also used to reduce the risk of major adverse cardiovascular events (MACE) in patients with established cardiovascular disease. The use of EMPEXEL 10 TABLET has been associated with several benefits, including improved glycemic control, reduced blood pressure, and decreased body weight. The medication has also been shown to reduce the risk of hospitalization for heart failure and the risk of renal disease progression. Additionally, empagliflozin has been found to have a neutral effect on lipid profiles, which is an advantage over some other antidiabetic medications. The medication can be used in patients with mild to moderate renal impairment, but the dose may need to be adjusted based on the patient's renal function. It is essential to monitor patients regularly while they are taking EMPEXEL 10 TABLET to ensure that the medication is effective and to minimize the risk of adverse effects.

Benefits

The use of EMPEXEL 10 TABLET has been associated with several benefits, including improved glycemic control, reduced blood pressure, and decreased body weight. The medication has also been shown to reduce the risk of major adverse cardiovascular events (MACE) in patients with established cardiovascular disease. Additionally, empagliflozin has been found to have a neutral effect on lipid profiles, which is an advantage over some other antidiabetic medications. The medication can be used in patients with mild to moderate renal impairment, but the dose may need to be adjusted based on the patient's renal function. EMPEXEL 10 TABLET has also been shown to reduce the risk of hospitalization for heart failure and the risk of renal disease progression. The benefits of EMPEXEL 10 TABLET are thought to be due to its unique mechanism of action, which involves the inhibition of sodium-glucose cotransporter 2 (SGLT2) in the kidneys. This leads to a reduction in glucose reabsorption and an increase in glucose excretion in the urine, resulting in improved glycemic control. The medication has also been shown to have beneficial effects on blood pressure and body weight, which are thought to be due to the increased excretion of sodium and water in the urine. Additionally, empagliflozin has been found to have anti-inflammatory and anti-oxidant effects, which may contribute to its beneficial effects on cardiovascular and renal outcomes. Overall, the benefits of EMPEXEL 10 TABLET make it a valuable treatment option for patients with type 2 diabetes.

Side Effects

The use of EMPEXEL 10 TABLET has been associated with several side effects, including hypoglycemia, genital mycotic infections, and increased urination. The medication can also cause dehydration, particularly in patients who are prone to dehydration or have a history of renal impairment. Additionally, empagliflozin has been associated with an increased risk of urinary tract infections, including pyelonephritis and urosepsis. The medication can also cause a decrease in blood pressure, which can increase the risk of dizziness and fainting. It is essential to monitor patients regularly while they are taking EMPEXEL 10 TABLET to minimize the risk of adverse effects. The side effects of EMPEXEL 10 TABLET can be managed by adjusting the dose or discontinuing the medication if necessary. Patients should be advised to drink plenty of water to stay hydrated, particularly in hot weather or when engaging in strenuous physical activity. Additionally, patients should be advised to monitor their blood glucose levels regularly and to report any signs or symptoms of hypoglycemia, such as dizziness, shaking, or sweating. The medication can also cause a decrease in renal function, particularly in patients with pre-existing renal impairment. It is essential to monitor renal function regularly while taking EMPEXEL 10 TABLET and to adjust the dose accordingly. Overall, the side effects of EMPEXEL 10 TABLET can be managed with proper monitoring and dose adjustment.

How To Use

EMPEXEL 10 TABLET should be taken once daily, with or without food. The medication should be swallowed whole with a glass of water, and patients should not chew or crush the tablet. The dose of EMPEXEL 10 TABLET can be adjusted based on the patient's renal function and response to treatment. Patients should be advised to take the medication at the same time every day to maintain a consistent level of empagliflozin in the blood. Additionally, patients should be advised to monitor their blood glucose levels regularly and to report any signs or symptoms of hypoglycemia, such as dizziness, shaking, or sweating. The use of EMPEXEL 10 TABLET requires regular monitoring of blood glucose levels, renal function, and urine glucose levels. Patients should be advised to keep a record of their blood glucose levels and to report any changes to their healthcare provider. Additionally, patients should be advised to monitor their weight and blood pressure regularly, as empagliflozin can cause changes in these parameters. The medication can be used in combination with other antidiabetic medications, such as metformin, sulfonylureas, or insulin, but the dose may need to be adjusted based on the patient's response to treatment. It is essential to follow the dosage instructions provided by the healthcare provider and to attend regular follow-up appointments to ensure that the medication is effective and to minimize the risk of adverse effects.

How It Works

EMPEXEL 10 TABLET works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, which reduces glucose reabsorption and increases glucose excretion in the urine. This leads to a decrease in blood glucose levels and an improvement in glycemic control. The medication also has beneficial effects on blood pressure and body weight, which are thought to be due to the increased excretion of sodium and water in the urine. Additionally, empagliflozin has been found to have anti-inflammatory and anti-oxidant effects, which may contribute to its beneficial effects on cardiovascular and renal outcomes. The mechanism of action of EMPEXEL 10 TABLET is unique compared to other antidiabetic medications. The medication works independently of insulin, which means that it can be used in patients with type 2 diabetes who have a reduced insulin response. The medication also has a low risk of hypoglycemia, particularly when used as monotherapy, which makes it a valuable treatment option for patients who are at risk of hypoglycemia. Additionally, empagliflozin has been shown to have beneficial effects on cardiovascular and renal outcomes, which makes it a valuable treatment option for patients with type 2 diabetes who are at risk of these complications. Overall, the mechanism of action of EMPEXEL 10 TABLET makes it a valuable treatment option for patients with type 2 diabetes.

Precautions

The use of EMPEXEL 10 TABLET requires several precautions, including regular monitoring of blood glucose levels, renal function, and urine glucose levels. Patients should be advised to monitor their weight and blood pressure regularly, as empagliflozin can cause changes in these parameters. The medication can increase the risk of hypoglycemia, particularly when used in combination with other antidiabetic medications, and patients should be advised to report any signs or symptoms of hypoglycemia, such as dizziness, shaking, or sweating. Additionally, patients should be advised to stay hydrated, particularly in hot weather or when engaging in strenuous physical activity, as the medication can cause dehydration. The precautions for EMPEXEL 10 TABLET also include the risk of genital mycotic infections, which can occur in patients taking the medication. Patients should be advised to practice good hygiene and to report any signs or symptoms of genital mycotic infections, such as itching, burning, or discharge. The medication can also increase the risk of urinary tract infections, including pyelonephritis and urosepsis, and patients should be advised to report any signs or symptoms of these infections, such as pain or burning during urination, or fever. Overall, the precautions for EMPEXEL 10 TABLET require regular monitoring and patient education to minimize the risk of adverse effects and to ensure that the medication is effective.

Warnings & Contraindications

The use of EMPEXEL 10 TABLET requires caution in several patient populations, including patients with renal impairment, patients with a history of diabetic ketoacidosis, and patients with a history of genital mycotic infections. The medication can increase the risk of hypoglycemia, particularly in patients who are taking other antidiabetic medications, and patients should be advised to monitor their blood glucose levels regularly. Additionally, the medication can cause dehydration, particularly in patients who are prone to dehydration or have a history of renal impairment, and patients should be advised to stay hydrated, particularly in hot weather or when engaging in strenuous physical activity. The caution for EMPEXEL 10 TABLET also includes the risk of cardiovascular events, including heart attack, stroke, and cardiac arrhythmias. Patients should be advised to report any signs or symptoms of cardiovascular events, such as chest pain, shortness of breath, or dizziness. The medication can also increase the risk of renal impairment, particularly in patients with pre-existing renal disease, and patients should be advised to monitor their renal function regularly. Overall, the caution for EMPEXEL 10 TABLET requires careful patient selection, regular monitoring, and patient education to minimize the risk of adverse effects and to ensure that the medication is effective.

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