DEBILIPTIN M TABLETS
Category: Diabetes Medicines
Brand: Ajanta Pharma Limited
Composition / Active Salts
Price: ₹60.90
MRP: ₹121.80 (50% OFF)
Inclusive of 5% GST
Pack Size: A pack of 10 Tablets
Availability: In Stock
Description
Debiliptin M Tablets are a combination medication used to treat type 2 diabetes mellitus. The tablets contain two active ingredients: Metformin and Teneligliptin. Metformin belongs to the class of biguanides and works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood sugar levels. Teneligliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps to increase the levels of incretin hormones, which in turn stimulates the release of insulin and decreases the production of glucose in the liver. The combination of these two ingredients provides a synergistic effect, allowing for better control of blood sugar levels.
The composition of Debiliptin M Tablets is 500mg of Metformin and 20mg of Teneligliptin. This combination is available in tablet form and is usually taken orally, once or twice a day, with or without food. The dosage may vary depending on the patient's condition, age, and other factors, and should be determined by a healthcare professional. It is essential to take the medication exactly as prescribed and not to skip or miss doses, as this can affect the efficacy of the treatment. Debiliptin M Tablets are typically prescribed for patients with type 2 diabetes who have not responded adequately to diet and exercise alone, or who require additional medication to control their blood sugar levels.
Uses & Indications
Debiliptin M Tablets are used to treat type 2 diabetes mellitus, a condition characterized by high blood sugar levels due to insulin resistance or impaired insulin secretion. The medication helps to control blood sugar levels, reducing the risk of complications associated with diabetes, such as heart disease, kidney damage, and nerve damage. Debiliptin M Tablets can be used as monotherapy or in combination with other anti-diabetic medications, such as sulfonylureas, thiazolidinediones, or insulin. The medication is also used to improve insulin sensitivity, which can help to reduce the risk of cardiovascular disease and other conditions associated with insulin resistance.
Debiliptin M Tablets are particularly useful for patients who have not responded adequately to metformin alone, as the addition of teneligliptin can provide additional glucose-lowering effects. The medication can also be used in patients with renal impairment, as teneligliptin has been shown to be effective and safe in patients with mild to moderate renal impairment. However, the dosage of Debiliptin M Tablets may need to be adjusted in patients with severe renal impairment. The medication is not recommended for patients with type 1 diabetes or diabetic ketoacidosis, as it is not effective in these conditions.
Benefits
Debiliptin M Tablets offer several benefits for patients with type 2 diabetes. One of the primary benefits is the ability to control blood sugar levels, which can help to reduce the risk of complications associated with diabetes. The medication has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, a measure of average blood sugar control over time. Debiliptin M Tablets also have a low risk of hypoglycemia, a common side effect of many anti-diabetic medications. This makes the medication a good option for patients who are at risk of hypoglycemia or who have a history of hypoglycemic episodes.
Another benefit of Debiliptin M Tablets is their ability to improve insulin sensitivity, which can help to reduce the risk of cardiovascular disease and other conditions associated with insulin resistance. The medication has also been shown to have a neutral effect on body weight, which is an advantage over some other anti-diabetic medications that can cause weight gain. Debiliptin M Tablets are also convenient to use, as they are available in a single tablet formulation, which can improve patient compliance and reduce the risk of medication errors. Overall, Debiliptin M Tablets offer a safe and effective treatment option for patients with type 2 diabetes, with a range of benefits that can help to improve blood sugar control and reduce the risk of complications.
Side Effects
Debiliptin M Tablets can cause a range of side effects, some of which are common and mild, while others are less common and more serious. Common side effects of the medication include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal pain. These side effects are usually mild and temporary, but can be unpleasant and may affect the patient's quality of life. Other common side effects of Debiliptin M Tablets include headache, dizziness, and fatigue. These side effects are usually dose-related and may resolve on their own over time.
Less common but more serious side effects of Debiliptin M Tablets include hypoglycemia, pancreatitis, and renal impairment. Hypoglycemia is a rare but potentially serious side effect of the medication, particularly when used in combination with other anti-diabetic medications. Pancreatitis is a rare but potentially life-threatening side effect of teneligliptin, which can cause severe abdominal pain, nausea, and vomiting. Renal impairment is a rare but potentially serious side effect of metformin, which can cause a range of symptoms including fatigue, weakness, and shortness of breath. Patients taking Debiliptin M Tablets should be monitored regularly for signs of these side effects and should seek medical attention immediately if they experience any symptoms.
How To Use
Debiliptin M Tablets should be taken exactly as prescribed by a healthcare professional. The medication is usually taken orally, once or twice a day, with or without food. The dosage of Debiliptin M Tablets may vary depending on the patient's condition, age, and other factors, and should be determined by a healthcare professional. Patients should not skip or miss doses, as this can affect the efficacy of the treatment. If a dose is missed, the patient should take the next dose at the usual time and should not take a double dose to make up for the missed dose.
Patients taking Debiliptin M Tablets should also follow a healthy diet and exercise regularly to help control their blood sugar levels. The medication should be taken in combination with a healthy lifestyle, including a balanced diet and regular physical activity. Patients should also monitor their blood sugar levels regularly and should seek medical attention immediately if they experience any symptoms of hypoglycemia or other side effects. Debiliptin M Tablets can be taken with other medications, but patients should inform their healthcare professional about all the medications they are taking, including prescription and non-prescription medications, vitamins, and herbal supplements.
How It Works
Debiliptin M Tablets work by combining the effects of metformin and teneligliptin, two medications that have different mechanisms of action. Metformin works by decreasing glucose production in the liver, increasing insulin sensitivity, and thereby lowering blood sugar levels. Teneligliptin, on the other hand, works by increasing the levels of incretin hormones, which stimulate the release of insulin and decrease the production of glucose in the liver. The combination of these two medications provides a synergistic effect, allowing for better control of blood sugar levels.
The mechanism of action of Debiliptin M Tablets involves the inhibition of dipeptidyl peptidase-4 (DPP-4), an enzyme that breaks down incretin hormones. By inhibiting DPP-4, teneligliptin increases the levels of incretin hormones, which in turn stimulates the release of insulin and decreases the production of glucose in the liver. Metformin, on the other hand, works by activating adenosine monophosphate-activated protein kinase (AMPK), an enzyme that regulates glucose and lipid metabolism. The activation of AMPK leads to a decrease in glucose production in the liver and an increase in insulin sensitivity, resulting in lower blood sugar levels.
Precautions
Debiliptin M Tablets should be used with caution in patients with certain medical conditions, including renal impairment, liver disease, and heart failure. Patients with renal impairment should be monitored regularly for signs of worsening renal function, as metformin can cause a decrease in renal function. Patients with liver disease should be monitored regularly for signs of worsening liver function, as teneligliptin can cause an increase in liver enzymes. Patients with heart failure should be monitored regularly for signs of worsening heart failure, as metformin can cause a decrease in cardiac function.
Patients taking Debiliptin M Tablets should also be cautious when taking other medications, including cationic medications such as digoxin and cimetidine, which can interact with metformin. Patients should inform their healthcare professional about all the medications they are taking, including prescription and non-prescription medications, vitamins, and herbal supplements. Debiliptin M Tablets should not be used in patients with type 1 diabetes or diabetic ketoacidosis, as they are not effective in these conditions. Patients should also be cautious when driving or operating heavy machinery, as Debiliptin M Tablets can cause dizziness and hypoglycemia.
Warnings & Contraindications
Debiliptin M Tablets should be used with caution in patients with a history of hypoglycemia, as the medication can cause hypoglycemia, particularly when used in combination with other anti-diabetic medications. Patients should be monitored regularly for signs of hypoglycemia, including shakiness, dizziness, sweating, and confusion. Patients should also be cautious when taking Debiliptin M Tablets with other medications that can cause hypoglycemia, such as sulfonylureas and insulin.
Patients taking Debiliptin M Tablets should also be cautious when experiencing stress, such as fever, trauma, or surgery, as these conditions can cause a decrease in blood sugar levels. Patients should inform their healthcare professional about any stress they are experiencing, as the dosage of Debiliptin M Tablets may need to be adjusted. Debiliptin M Tablets should not be used in patients with a history of pancreatitis, as teneligliptin can cause pancreatitis. Patients should be monitored regularly for signs of pancreatitis, including severe abdominal pain, nausea, and vomiting. Patients should seek medical attention immediately if they experience any symptoms of pancreatitis or other serious side effects.
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