DAPARES M 10/500 TABLET 10S
Category: Diabetes Medicines
Brand: CELERA HEALTHCARE PVT LTD
Composition / Active Salts
Price: ₹89.25
MRP: ₹111.56 (20% OFF)
Inclusive of 5% GST
Pack Size: A pack of 10 Tablets
Availability: In Stock
Description
Dapares M 10/500 Tablet 10s is a combination medication that contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin belongs to a class of medications known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, which work by preventing the kidneys from reabsorbing glucose back into the bloodstream, thereby increasing the amount of glucose excreted in the urine. Metformin, on the other hand, is a biguanide that decreases glucose production in the liver and increases insulin sensitivity, allowing glucose to enter the cells more efficiently. The combination of these two medications provides a synergistic effect, allowing for better control of blood glucose levels.
The medication is available in tablet form, with each tablet containing 10mg of Dapagliflozin and 500mg of Metformin. The tablets are designed to be taken orally, once or twice a day, depending on the patient's specific needs and medical condition. The medication is typically prescribed for patients with type 2 diabetes mellitus, who are unable to control their blood glucose levels through diet and exercise alone. The combination of Dapagliflozin and Metformin has been shown to be effective in reducing hemoglobin A1c (HbA1c) levels, as well as improving insulin sensitivity and reducing body weight.
Uses & Indications
Dapares M 10/500 Tablet 10s is primarily used to treat type 2 diabetes mellitus in adults. The medication is designed to be used in conjunction with diet and exercise, and is typically prescribed for patients who are unable to achieve adequate glycemic control through lifestyle modifications alone. The medication can be used as a monotherapy, or in combination with other anti-diabetic medications, such as sulfonylureas, thiazolidinediones, or insulin. The combination of Dapagliflozin and Metformin has been shown to be effective in reducing the risk of major adverse cardiovascular events (MACE) in patients with type 2 diabetes and established cardiovascular disease.
In addition to its use in treating type 2 diabetes, Dapares M 10/500 Tablet 10s may also be used to treat other conditions, such as polycystic ovary syndrome (PCOS) and non-alcoholic fatty liver disease (NAFLD). The medication has been shown to improve insulin sensitivity and reduce androgen levels in women with PCOS, and may also help to reduce liver fat and improve liver function in patients with NAFLD. However, these uses are not FDA-approved, and the medication should only be used for these indications under the guidance of a qualified healthcare professional.
Benefits
The combination of Dapagliflozin and Metformin in Dapares M 10/500 Tablet 10s provides several benefits for patients with type 2 diabetes. One of the primary benefits is the ability to improve glycemic control, as measured by reductions in HbA1c levels. The medication has been shown to reduce HbA1c levels by 1-2% compared to placebo, which can help to reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, kidney disease, and nerve damage. Additionally, the medication has been shown to improve insulin sensitivity, which can help to reduce the amount of insulin required to control blood glucose levels.
Another benefit of Dapares M 10/500 Tablet 10s is its ability to promote weight loss. The medication has been shown to reduce body weight by 2-5% compared to placebo, which can help to improve insulin sensitivity and reduce the risk of cardiovascular disease. The medication has also been shown to reduce blood pressure and improve lipid profiles, which can help to reduce the risk of cardiovascular disease. Overall, the combination of Dapagliflozin and Metformin in Dapares M 10/500 Tablet 10s provides a comprehensive approach to managing type 2 diabetes, and can help to improve glycemic control, promote weight loss, and reduce the risk of long-term complications.
Side Effects
Dapares M 10/500 Tablet 10s can cause several side effects, some of which are common and mild, while others are rare and more serious. Common side effects of the medication include increased urination, thirst, and genital mycotic infections. These side effects are typically mild and temporary, and can be managed by increasing fluid intake and practicing good hygiene. Less common side effects of the medication include hypoglycemia (low blood sugar), diarrhea, and nausea. These side effects can be more serious, and may require medical attention if they persist or worsen over time.
Rare but more serious side effects of Dapares M 10/500 Tablet 10s include kidney problems, such as acute kidney injury or kidney failure, and increased risk of amputations. The medication can also increase the risk of diabetic ketoacidosis, a serious condition that occurs when the body produces high levels of blood acids called ketones. Patients taking the medication should be aware of the signs and symptoms of these side effects, and should seek medical attention immediately if they experience any unusual or severe symptoms. Additionally, patients should be monitored regularly for signs of kidney problems, and should have their kidney function tested before starting the medication and periodically thereafter.
How To Use
Dapares M 10/500 Tablet 10s should be taken orally, once or twice a day, depending on the patient's specific needs and medical condition. The medication should be taken with food, and should be swallowed whole with a full glass of water. Patients should not crush or chew the tablets, as this can affect the way the medication is absorbed by the body. The medication should be taken at the same time every day, and patients should try to establish a regular routine to help them remember to take their medication.
Patients should also be aware of the importance of monitoring their blood glucose levels regularly while taking Dapares M 10/500 Tablet 10s. This can help to ensure that the medication is working effectively, and can also help to identify any potential side effects or interactions with other medications. Patients should also be aware of the signs and symptoms of hypoglycemia (low blood sugar), and should know how to treat it if it occurs. Additionally, patients should be aware of the importance of staying hydrated while taking the medication, as it can increase the risk of dehydration and kidney problems.
How It Works
Dapares M 10/500 Tablet 10s works by combining the actions of two separate medications: Dapagliflozin and Metformin. Dapagliflozin works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys, which reduces the amount of glucose reabsorbed by the kidneys and increases the amount of glucose excreted in the urine. This helps to reduce blood glucose levels and improve glycemic control. Metformin, on the other hand, works by decreasing glucose production in the liver and increasing insulin sensitivity, allowing glucose to enter the cells more efficiently.
The combination of Dapagliflozin and Metformin in Dapares M 10/500 Tablet 10s provides a synergistic effect, allowing for better control of blood glucose levels. The medication has been shown to reduce HbA1c levels, improve insulin sensitivity, and reduce body weight, all of which can help to reduce the risk of long-term complications associated with diabetes. The medication has also been shown to reduce blood pressure and improve lipid profiles, which can help to reduce the risk of cardiovascular disease. Overall, the combination of Dapagliflozin and Metformin in Dapares M 10/500 Tablet 10s provides a comprehensive approach to managing type 2 diabetes.
Precautions
Patients taking Dapares M 10/500 Tablet 10s should be aware of several precautions to minimize the risk of side effects and interactions with other medications. One of the most important precautions is to stay hydrated, as the medication can increase the risk of dehydration and kidney problems. Patients should drink plenty of water and other fluids, and should avoid activities that can cause dehydration, such as excessive exercise or exposure to high temperatures. Patients should also be aware of the signs and symptoms of hypoglycemia (low blood sugar), and should know how to treat it if it occurs.
Patients should also be aware of the potential for interactions with other medications, including diuretics, blood thinners, and other medications that can affect blood glucose levels. Patients should inform their healthcare provider of all medications they are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements. Additionally, patients should be aware of the potential for allergic reactions, and should seek medical attention immediately if they experience any unusual or severe symptoms, such as rash, itching, or difficulty breathing. Patients should also have their kidney function tested before starting the medication and periodically thereafter, as the medication can increase the risk of kidney problems.
Warnings & Contraindications
Dapares M 10/500 Tablet 10s should be used with caution in certain patient populations, including patients with kidney problems, liver disease, or heart failure. The medication can increase the risk of kidney problems, including acute kidney injury or kidney failure, and should be used with caution in patients with pre-existing kidney disease. Patients with liver disease should also use the medication with caution, as it can increase the risk of lactic acidosis, a rare but serious condition that can be fatal.
Patients with heart failure should also use the medication with caution, as it can increase the risk of worsening heart failure. The medication should not be used in patients with type 1 diabetes, as it can increase the risk of diabetic ketoacidosis, a serious condition that can be fatal. Patients should also be aware of the potential for increased risk of amputations, particularly in patients with a history of prior amputation, peripheral artery disease, or foot ulcers. Patients should monitor their feet regularly and seek medical attention immediately if they experience any signs or symptoms of foot problems, such as pain, tenderness, or swelling.
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