AZIPRO 250 TABLET
Category: Anti-Infective Medicines
Brand: ABBOTT HEALTHCARE PVT LTD
Composition / Active Salts
Price: ₹51.68
MRP: ₹73.83 (30% OFF)
Inclusive of 5% GST
Pack Size: A pack of 6 Tablets
Availability: In Stock
Description
Azithromycin is a macrolide antibiotic that is used to treat various bacterial infections, including respiratory tract infections, skin infections, and sexually transmitted diseases. The AZIPRO 250 TABLET contains 250mg of Azithromycin, which is the active ingredient responsible for its therapeutic effects. This medication works by inhibiting the growth of bacteria, ultimately leading to their death. The mechanism of action involves the binding of Azithromycin to the bacterial ribosome, which is the site of protein synthesis. This binding inhibits the translation of messenger RNA into proteins, which are essential for the survival of the bacteria.
The AZIPRO 250 TABLET is a white, film-coated tablet that is designed for oral administration. It is usually taken once daily, with or without food, for a period of 3 to 5 days, depending on the type and severity of the infection being treated. The tablet should be swallowed whole, without crushing or chewing, to ensure that the medication is released slowly and evenly into the bloodstream. The pharmacokinetics of Azithromycin are characterized by a high bioavailability, which means that a significant proportion of the dose is absorbed into the bloodstream. The medication is then distributed to various tissues and organs, where it exerts its antibacterial effects.
Uses & Indications
The AZIPRO 250 TABLET is used to treat a wide range of bacterial infections, including acute bacterial sinusitis, community-acquired pneumonia, pharyngitis, and tonsillitis. It is also used to treat skin and soft tissue infections, such as uncomplicated skin and skin structure infections, and genital infections, including chlamydia and gonorrhea. In addition, Azithromycin is used to treat certain types of infections in patients with chronic obstructive pulmonary disease (COPD) and cystic fibrosis. The medication is effective against a variety of bacterial pathogens, including Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus.
The AZIPRO 250 TABLET is also used to treat certain types of infections in children, including acute otitis media, community-acquired pneumonia, and pharyngitis. The medication is available in various strengths, including 250mg and 500mg tablets, which allows for flexible dosing regimens. The choice of dose and duration of treatment depends on the type and severity of the infection, as well as the patient's age, weight, and renal function. In general, the medication is well-tolerated and effective in treating bacterial infections, with a low incidence of adverse effects and a high rate of clinical success.
Benefits
The AZIPRO 250 TABLET has several benefits that make it a popular choice for the treatment of bacterial infections. One of the main benefits is its broad-spectrum antibacterial activity, which allows it to effectively treat a wide range of infections. The medication is also characterized by a long half-life, which means that it can be taken once daily, reducing the risk of non-adherence and improving patient compliance. Additionally, Azithromycin has a low incidence of adverse effects, particularly when compared to other antibiotics, such as penicillins and cephalosporins.
The AZIPRO 250 TABLET is also convenient to use, as it can be taken with or without food, and it does not require dose adjustment in patients with renal impairment. The medication is also available in a variety of strengths, which allows for flexible dosing regimens and makes it suitable for use in patients of all ages. Furthermore, Azithromycin has been shown to have immunomodulatory effects, which may help to reduce the severity of certain infections and improve clinical outcomes. Overall, the AZIPRO 250 TABLET is a valuable addition to the treatment armamentarium for bacterial infections, offering a convenient, effective, and well-tolerated treatment option.
Side Effects
The AZIPRO 250 TABLET is generally well-tolerated, but it can cause some side effects, particularly when taken in high doses or for extended periods. The most common side effects include gastrointestinal symptoms, such as nausea, vomiting, diarrhea, and abdominal pain. These symptoms are usually mild and self-limiting, but they can be severe in some cases. Other side effects include headache, dizziness, and fatigue, which are also usually mild and transient.
In rare cases, the AZIPRO 250 TABLET can cause more serious side effects, such as allergic reactions, including anaphylaxis and Stevens-Johnson syndrome. These reactions are characterized by symptoms such as rash, itching, swelling, and difficulty breathing, and they require immediate medical attention. The medication can also cause liver damage, including elevated liver enzymes and hepatitis, particularly when taken in high doses or for extended periods. In addition, Azithromycin can cause cardiac arrhythmias, including QT interval prolongation, which can increase the risk of torsades de pointes and other serious cardiac events.
How To Use
The AZIPRO 250 TABLET should be taken exactly as directed by the healthcare provider. The medication is usually taken once daily, with or without food, for a period of 3 to 5 days, depending on the type and severity of the infection being treated. The tablet should be swallowed whole, without crushing or chewing, to ensure that the medication is released slowly and evenly into the bloodstream. It is also important to complete the full course of treatment, even if symptoms improve before the end of the treatment period, to ensure that the infection is fully cleared.
The AZIPRO 250 TABLET can be taken with or without food, but it is recommended to take it with food to reduce the risk of gastrointestinal side effects. The medication should be taken at the same time every day, to help maintain a consistent level of the medication in the bloodstream. It is also important to drink plenty of water while taking the medication, to help prevent dehydration and reduce the risk of kidney damage. In addition, patients should avoid taking the medication with other drugs that can interact with Azithromycin, such as antacids and certain antibiotics, to reduce the risk of adverse effects.
How It Works
The AZIPRO 250 TABLET works by inhibiting the growth of bacteria, ultimately leading to their death. The mechanism of action involves the binding of Azithromycin to the bacterial ribosome, which is the site of protein synthesis. This binding inhibits the translation of messenger RNA into proteins, which are essential for the survival of the bacteria. The medication is effective against a wide range of bacterial pathogens, including Gram-positive and Gram-negative bacteria, as well as certain types of atypical bacteria.
The AZIPRO 250 TABLET has a unique mechanism of action that allows it to accumulate in high concentrations within bacterial cells. This accumulation is due to the lipophilic nature of the medication, which allows it to penetrate the bacterial cell membrane and bind to the ribosome. The medication also has a long half-life, which allows it to remain in the bloodstream for an extended period, providing a prolonged antibacterial effect. This prolonged effect allows for once-daily dosing, which improves patient compliance and reduces the risk of non-adherence.
Precautions
The AZIPRO 250 TABLET should be used with caution in certain patients, particularly those with a history of allergic reactions to macrolide antibiotics. The medication can cause allergic reactions, including anaphylaxis and Stevens-Johnson syndrome, which can be life-threatening. Patients should be monitored closely for signs of an allergic reaction, such as rash, itching, and difficulty breathing, and the medication should be discontinued immediately if any of these symptoms occur.
The AZIPRO 250 TABLET should also be used with caution in patients with certain medical conditions, such as liver disease, kidney disease, and heart disease. The medication can cause liver damage, including elevated liver enzymes and hepatitis, particularly when taken in high doses or for extended periods. Patients with liver disease should be monitored closely for signs of liver damage, and the medication should be discontinued immediately if any of these symptoms occur. In addition, the medication can cause cardiac arrhythmias, including QT interval prolongation, which can increase the risk of torsades de pointes and other serious cardiac events.
Warnings & Contraindications
The AZIPRO 250 TABLET should be used with caution in certain situations, particularly when taken with other medications that can interact with Azithromycin. The medication can interact with certain antibiotics, such as antacids and certain cephalosporins, which can reduce its effectiveness or increase the risk of adverse effects. Patients should be advised to avoid taking the medication with other drugs that can interact with Azithromycin, and to inform their healthcare provider of any medications they are taking before starting treatment.
The AZIPRO 250 TABLET should also be used with caution in patients who are pregnant or breastfeeding, as the safety of the medication in these populations has not been established. The medication can cross the placenta and enter the fetal circulation, which can increase the risk of birth defects and other adverse effects. In addition, the medication can be excreted in breast milk, which can increase the risk of adverse effects in nursing infants. Patients who are pregnant or breastfeeding should be advised to inform their healthcare provider before starting treatment, and to discuss the potential risks and benefits of the medication.
Generic Alternatives
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- ROWEZY 250 10 TABLET — ₹53.44 | Jagsonpal Pharmaceuticals Ltd
- AZIPRO 250MG 6 TABLET — ₹61.37 | Cipla Ltd
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- AZIMAX 250MG 6 TABLET — ₹70.69 | Cipla Ltd
- AZIBEST 250MG TABLET — ₹71.25 | Blue Cross Laboratories Ltd
- LAZ 250MG 6 TABLET — ₹71.72 | HETERO HEALTH CARE LTD